Preheat your oven to 350°F (175°C).
In a large bowl, combine cooked pasta, protein, and mixed vegetables.
Add the cream of mushroom soup and mix until well combined.
Season with garlic powder, onion powder, salt, and pepper.
Transfer the mixture to a greased casserole dish.
Sprinkle shredded cheese evenly over the top.
If desired, add breadcrumbs for extra crunch.
Cover with aluminum foil and bake for 20 minutes.
Remove the foil and bake for an additional 10 minutes, or until cheese is bubbly and golden.
Let it cool for a few minutes before serving.