Season the chuck roast with salt, pepper, garlic powder, and onion powder.
Heat a skillet over medium-high heat and sear the roast on all sides until browned.
Place the chopped carrots, potatoes, and quartered onion in the bottom of the crockpot.
Transfer the seared roast to the crockpot, placing it on top of the vegetables.
In a bowl, mix beef broth and Worcestershire sauce, then pour over the roast.
Cover the crockpot with its lid and set it to low for 8 hours or high for 4 hours.
Once cooked, check the tenderness of the meat; it should easily shred with a fork.
Remove the roast and vegetables, and let rest for a few minutes before slicing.
Thicken the remaining liquid in the crockpot for gravy, if desired.
Serve the sliced roast with the vegetables and drizzle with gravy.